Monoclonal Antibodies which Preferentially Bind to 22K Human Growth Hormone Rather than Its 20k Variant.
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چکیده
منابع مشابه
Monoclonal antibodies which preferentially bind to 22 K human growth hormone rather than its 20 K variant.
We have established 13 hybridoma cell lines which secrete mouse IgG1 monoclonal antibodies (McAbs) to human growth hormone (hGH). Binding affinity and binding specificity of McAbs were analyzed by competitive radioimmunoassay. Among these McAbs, CL. B1 showed a high affinity of 9.8 x 10(8) l/mol, and all McAbs so far tested showed very weak cross-reactivity or none at all with human prolactin (...
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ژورنال
عنوان ژورنال: Endocrinologia Japonica
سال: 1989
ISSN: 0013-7219,2185-6370
DOI: 10.1507/endocrj1954.36.481